New Approaches to Oxirane Containing Natural Products: Stereoselective Total Synthesis of the Antitumor Agents Gummiferol and Depudecin

La comunicación presenta la síntesis total de productos naturales con actividad antitumoral caracterizados estructuralmente por la presencia de anillos de oxirano. Para ello se empleó una nueva metodología de epoxidación asimétrica basada en una nueva clase de iluros de azufre quirales. Mediante esta metodología se realizaron las síntesis de los productos naturales Gummiferol y DepudecinaUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Cómo trabajar la educación emocional a través de la educación plástica

Resumen no disponibleGrado en Educación Primari

The role of advanced waste-To-energy technologies in landfill mining

Publicado en: WIT Transactions on Ecology and the Environment, Volume 224, Issue 1, 20 September 2017, Pages 403-409Recently, the European Parliament has decided to include a specific reference to "Enhanced Landfill Mining" (ELFM) in the Landfill Directive proposing a regulatory framework for ELFM so as to permit the retrieval of secondary raw materials that are present in existing landfill sites. Recent studies are supporting ELFM since they consider that landfill mining would be economically feasible only if combined with energy recovery (i.e., waste-To-energy, WtE) and if a wide range of materials are recovered (i.e., waste-To-materials, WtM). In this study, a combined material (landfill mining) and energy (advanced WtE) recovery is proposed where the excavated waste (MSW refuse) can be directly recycled or pretreated and used in the production of refuse-derived fuel (RDF) for an advanced (gasification-based) WtE plant producing power and heat. Both material and energy recovery are challenging in the circular economy since contributes to a loop-closing objective in human activities. An exhaustive assessment of each particular landfill site must be carried out in order to determine the profitability of the ELFM.Ministerio de Economía y Competitividad ENE2012-31598Ministerio de Ciencia, Innovación y Universidades CTM2016-78089-RUniversidad de Sevilla Contrato de Acceso al Sistema Español de Ciencia, Tecnología e Innovación (VPPI-US

Discrimination of milks with a multisensor system based on layer-by-layer films

Producción CientíficaA nanostructured electrochemical bi-sensor system for the analysis of milks has been developed using the layer-by-layer technique. The non-enzymatic sensor [CHI+IL/CuPcS]2, is a layered material containing a negative film of the anionic sulfonated copper phthalocyanine (CuPcS) acting as electrocatalytic material, and a cationic layer containing a mixture of an ionic liquid (IL) (1-butyl-3-methylimidazolium tetrafluoroborate) that enhances the conductivity, and chitosan (CHI), that facilitates the enzyme immobilization. The biosensor ([CHI+IL/CuPcS]2-GAO) results from the immobilization of galactose oxidase on the top of the LbL layers. FTIR, UV–vis, and AFM have confirmed the proposed structure and cyclic voltammetry has demonstrated the amplification caused by the combination of materials in the film. Sensors have been combined to form an electronic tongue for milk analysis. Principal component analysis has revealed the ability of the sensor system to discriminate between milk samples with different lactose content. Using a PLS-1 calibration models, correlations have been found between the voltammetric signals and chemical parameters measured by classical methods. PLS-1 models provide excellent correlations with lactose content. Additional information about other components, such as fats, proteins, and acidity, can also be obtained. The method developed is simple, and the short response time permits its use in assaying milk samples online.Ministerio de Economía, Industria y Competitividad - Fondo Europeo de Desarrollo Regional (project AGL2015-67482-R)Junta de Castilla y Leon - Fondo Europeo de Desarrollo Regional (project VA-011U16)Junta de Castilla y León (grant BOCYL-D-4112015-9

Improvement of biomethane potential of sewage sludge anaerobic co-digestion by addition of “sherry-wine” distillery wastewater

Co-digestion of sewage sludge (SS) with other unusually treated residues has been reported as an efficient method to improve biomethane production. In this work, Sherry-wine distillery wastewater (SWDW) has been proposed as co-substrate in order to increase biomethane production and as a breakthrough solution in the management of both types of waste. In order to achieve this goal, different SS:SW-DW mixtures were employed as substrates in Biomethane Potential (BMP) tests. The biodegradability and biomethane potential of each mixture was determined selecting the optimal co-substrate ratio. Results showed that the addition of SW-DW as a co-substrate improves the anaerobic digestion of SS in a proportionally way in terms of CODs and biomethane production The optimal co-substrates ratio was 50:50 of SS:SW-DW obtaining %VSremoval ¼ 54.5%; YCH4 ¼ 225.1 L CH4/kgsv or 154 L CH4/kgCODt and microbial population of 5.5 times higher than sole SS. In this case, %VSremoval ¼ 48.1%; YCH4 ¼ 183 L CH4/ kgsv or 135 L CH4/kgCODt. The modified Gompertz equation was used for the kinetic modelling of biogas production with successful fitting results (r2 ¼ 0.99). In this sense, at optimal conditions, the maximum productivity reached at an infinite digestion time was (YMAX CH4 ) ¼ 229 ± 5.0 NL/kgSV; the specific constant was K ¼ 25.0 ± 2.3 NL/kgSV$d and the lag phase time constant was (l) ¼ 2.49 ± 0.1

Los cuidados enfermeros en la calidad de vida de las mujeres mastectomizadas

Introducción: El cáncer de mama afecta a una de cada ocho mujeres a lo largo de sus vidas. En Castilla y León se dan unos 10.000 casos nuevos cada año, casi 7000 fallecimientos y más de 17.000 hospitalizaciones. A pesar de ello, la supervivencia se ha incrementado un 1,4% anualmente y gracias a los programas de cribado, la mayoría de los casos se detectan entre los 35 y los 80 años, en estadios poco avanzados. Objetivo: El objetivo general es identificar la mejor evidencia de la atención enfermera en la calidad de vida de las mujeres mastectomizadas. Material y métodos: Se ha realizado una búsqueda bibliográfica sobre el tema en bases de datos, revistas de enfermería y páginas en salud. El periodo de búsqueda abarca desde Diciembre de 2014 a Mayo de 2015. Resultados y discusión: Se concretan las principales alteraciones psíquicas y físicas en las mujeres a las que se les ha sometido a una mastectomía. Se evidencia que los profesionales de enfermería son la fuente principal de información y apoyo para las mujeres mastectomizadas. Conclusiones: La ansiedad y la falta de información son los primeros retos a los que se enfrentan las pacientes, que derivan en otros más complejos como son: la depresión, la distorsión de la imagen corporal y la baja autoestima. El linfedema y el hombro doloroso, son los principales problemas físicos. Enfermería debe proporcionar la atención integral e individualizada que las pacientes necesitan, involucrando también a la familia, y para ello se hace necesaria una especialización en el cuidado.Grado en Enfermerí